MAPKAP Kinase 2, phosphorylated (Ser272) (Mitogen-activated Protein Kinase-activated Protein Kinase 2, MAP Kinase-activated Protein Kinase 2, MAPK-activated Protein Kinase 2, MAPKAPK2, MAPKAPK-2, MK2), Rabbit

Catalog Number: USB-M2355-01L
Article Name: MAPKAP Kinase 2, phosphorylated (Ser272) (Mitogen-activated Protein Kinase-activated Protein Kinase 2, MAP Kinase-activated Protein Kinase 2, MAPK-activated Protein Kinase 2, MAPKAPK2, MAPKAPK-2, MK2), Rabbit
Biozol Catalog Number: USB-M2355-01L
Supplier Catalog Number: M2355-01L
Alternative Catalog Number: USB-M2355-01L-200
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues surrounding Ser272 of human MAPKAPK2. UniProt Accession P49137. Species Sequence Homology: mouse and rabbit
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. Applications: Suitable for use in ELISA, Dot Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (FFPE): 1:50-1:100 Dot Blot: 1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 116584
UniProt: P49137
Purity: Purified by Protein A and peptide affinity chromatography.
Form: Supplied as a liquid in PBS, 0.09% sodium azide.