MAP3K9, CT (Mitogen-activated Protein Kinase Kinase Kinase 9, MEKK9, Mixed Lineage Kinase 1, MLK1, PRKE1), Rabbit
Catalog Number:
USB-M2350-16C
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| Article Name: | MAP3K9, CT (Mitogen-activated Protein Kinase Kinase Kinase 9, MEKK9, Mixed Lineage Kinase 1, MLK1, PRKE1), Rabbit |
| Biozol Catalog Number: | USB-M2350-16C |
| Supplier Catalog Number: | M2350-16C |
| Alternative Catalog Number: | USB-M2350-16C-200 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC, WB |
| Immunogen: | Synthetic peptide selected from the C-terminal region of human MLK1 (KLH). |
| MLK1 is a MLK(MAP3K) type protein kinase. The catalytic domain of mixed-lineage kinases (MLKs) kinases have amino acid sequence similarity to both the tyr-specific and the ser/thr-specific kinase classes. In addition to thee unusual nature of the kinase catalytic domains, MLK1 and MLK2 contain 2 leu/ile-zipper motifs and a basic sequence near their C-termini. MLK1 is a member of the neuronal apoptotic JNK/c-Jun pathway acting between Rac1/Cdc42 and MKK4 and -7 in death signaling. MLK1 expression has been documented in human epithelial tumor cell lines of colonic, breast and esophageal origin. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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