MAP2K4 (Ser257) (Dual Specificity Mitogen-activated Protein Kinase Kinase 4, MAP Kinase Kinase 4, MAPKK 4, MAPKK4, MKK4, JNK-activating Kinase 1, c-Jun N-terminal Kinase Kinase 1, JNKK1, JNKK, MAPK/ERK Kinase 4, MEK 4, MEK4, PRKMK
Catalog Number:
USB-M2350-04D
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| Article Name: | MAP2K4 (Ser257) (Dual Specificity Mitogen-activated Protein Kinase Kinase 4, MAP Kinase Kinase 4, MAPKK 4, MAPKK4, MKK4, JNK-activating Kinase 1, c-Jun N-terminal Kinase Kinase 1, JNKK1, JNKK, MAPK/ERK Kinase 4, MEK 4, MEK4, PRKMK |
| Biozol Catalog Number: | USB-M2350-04D |
| Supplier Catalog Number: | M2350-04D |
| Alternative Catalog Number: | USB-M2350-04D-200 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC, WB |
| Immunogen: | Synthetic non-phosphopeptide corresponding to amino acid residues surrounding Ser257of human MAP2K4 (KLH). |
| MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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