Desfluoro-ezetimibe is a defluorinated impurity of Ezetimibe, a cholesterol absorption inhibitor and Niemann-Pick C1-like1 (NPC1L1) inhibitor, demonstrating metabolic stability and Nrf2 activation, suitable for cardiovascular disease and antioxidant research. Synonyms: (3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenyl-2-azetidinone, 2-Azetidinone, 3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenyl-, (3R,4S)-, Desfluoro Ezetimibe, Etezimibe Desfluoroaniline analog CAS No: 302781-98-2 Molecular Formula: C24H22FNO3 Molecular Weight: 391.43 Appearance: White to off-white solid Purity: 99% (HPLC) Solubility: DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
391.43
Purity:
99% (HPLC)
Form:
White to off-white solid
CAS Number:
[302781-98-2]
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