NEK7 degrader-1, CAS [[3069891-91-1]] Preis auf Anfrage
Biozol Catalog Number:
TGM-TYD-05040
Supplier Catalog Number:
TYD-05040
Alternative Catalog Number:
TGM-TYD-05040-10MG, TGM-TYD-05040-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
NEK7degrader-1 (Compound 17) is a NEK7 degrader with a DC50 of 0.1 nM. It inhibits caspase-1 activity and IL-beta release in macrophages in a dose-dependent manner in response to NLRP3 inflammasome activation. NEK7degrader-1 is useful for researching autoinflammatory and autoimmune diseases (like multiple sclerosis), neurodegenerative disorders (such as Alzheimers disease), and cardiovascular and pigment diseases (including pericarditis and type 2 diabetes).
