Helix pomatia Agglutinin is a lectin discovered in the reproductive gland of the Roman snail and binds specifically to N-acetylgalactosamine (GalNAc). It exhibits high affinity for steroid hormones, specifically testosterone and progesterone, with a dissociation constant (kD) of 1.9-2.4 µM. Additionally, it interacts with adenine (kD = 5.4 µM) and 2-(p-toluidino)naphthalene-6-sulfonic acid (TNS) with a kD of 12 µM. This compound is frequently utilized in the characterization, imaging, or targeting of glyco-conjugates, making it an invaluable asset in glycomics analysis. It is also applicable in cancer prognosis research.
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