Kisspeptin antagonist p271 is a Kisspeptin inhibitor with cell-penetrating properties. It blocks the binding of endogenous Kisspeptin to GPR54 on pituitary growth hormone cells, removing the inhibition on growth hormone secretion. This compound specifically and significantly stimulates the release of growth hormone while inhibiting luteinizing hormone, without affecting prolactin or cortisol levels. Kisspeptin antagonist p271 may be used in research related to growth hormone deficiency disorders.
Target:
Kisspeptin
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