32-cGAMP (c[A(2,5)pG(3,5)p]) is an isomer of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP). It selectively activates fruit fly STING (dSTING), initiating the dSTING-NF-kappaB signaling pathway, driving the expression of Sting-regulated genes, and conferring a potent antiviral state in vivo. Additionally, 32-cGAMP resists cleavage by viral poxin and is useful in viral infection research.
Molecular Weight:
674.42
CAS Number:
[1615704-64-7]
Formula:
C20H24N10O13P2
Target:
STING|||NF-kappaB
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