Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 8.60 µM. It can be isolated from the fungus Penicillium sp. ZYX-Z-143. Additionally, Penpaxilloids A functions as an alpha-glucosidase inhibitor and demonstrates anti-inflammatory properties.
Formula:
C31H37NO7
Target:
Phosphatase|||glycosidase
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