NVP-DFV890 is an orally active and selective NLRP3 inflammasome inhibitor that directly binds to and inhibits NLRP3 activation, thereby blocking the maturation and release of IL-1beta and IL-18 and reducing pyroptotic cell death. NVP-DFV890 has shown immunomodulatory effects in viral infection and inflammatory models and is primarily investigated in COVID-19 and acute respiratory distress syndrome to attenuate excessive inflammatory responses.
Molecular Weight:
420.55
CAS Number:
[2271394-34-2]
Formula:
C19H24N4O3S2
Target:
NOD|||SARS-CoV
T88849
T88849
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