TP-050 is a chemical probe, which has oral activity and selectively acts on NMDAR. The EC50 of GluN2A and GluN2D are 0.51 µM and 9.6 µM respectively, and it can penetrate the blood-brain barrier. TP-050 can induce long-term potentiation effect (LTP) in hippocampus, thus promoting neuronal signal transmission.
Molecular Weight:
380.78
Purity:
99.61%
CAS Number:
[3085030-47-0]
Formula:
C16H15ClF2N6O
Target:
iGluR
T73491
T73491
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