MLKL-IN-5 is a potent small molecule inhibitor of MLKL. By specifically targeting MLKL, it prevents its phosphorylation by RIPK3 and subsequent oligomerization, thereby blocking the transmission of the necroptosis signaling pathway. It is an important pharmacological tool molecule for studying the pathological mechanisms of necroptosis in various inflammatory diseases, neurodegenerative diseases, and cancer.
Molecular Weight:
416.45
Purity:
98.77%
CAS Number:
[2755872-58-1]
Formula:
C18H20N6O4S
Target:
MLK
T73279
T73279
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