Norartocarpetin is a tyrosinase inhibitor with strong inhibitory activity against tyrosinase (IC50 = 0.47 µM). It can be used as an anti-browning agent in food-related research and also shows significant anti-tumor activity against human lung cancer NCI-H460 cells with an IC50 of 22 µM. Its anti-proliferative mechanisms mainly include regulating the Ras/Raf/MAPK signaling pathway, inducing mitochondria-dependent apoptosis, arresting the cell cycle at S phase, and inhibiting cell migration and invasion.
Molecular Weight:
286.24
Purity:
99.97%
CAS Number:
[520-30-9]
Formula:
C15H10O6
Target:
Apoptosis|||Ras|||MAPK|||Raf|||Tyrosinase
T72803
T72803
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