Beauveriolide III, a cyclodepsipeptide found in Beauveria fungi, inhibits lipid droplet formation (at 3-10 µM) and cholesterol synthesis (IC50=0.41 µM). This compound also suppresses acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity (IC50=5.5 µM) and reduces atherosclerotic lesion size in Ldlr-/- and ApoE-/- mouse models (25-50 mg/kg).
Molecular Weight:
487.63
Purity:
99.48%
CAS Number:
[221111-70-2]
Formula:
C27H41N3O5
Target:
Beta Amyloid
T36227
T36227
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