UB-MBX-46 is a potent and selective antagonist of the P2X7 receptor, with IC50 values of 0.514 nM (hP2X7R), 40.6 nM (rP2X7R), and 4.52 nM (mP2X7R). It interacts with the classical allosteric pocket of the human P2X7 receptor. UB-MBX-46 is applicable for research in cancer, atherosclerosis, and neurodegenerative diseases.
Target:
P2X Receptor
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