Keap1/Nrf2/ARE activator 2, CAS [[3105470-83-2]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T214303
Supplier Catalog Number:
T214303
Alternative Catalog Number:
TGM-T214303-10MG,TGM-T214303-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Keap1/Nrf2/ARE activator 2 is an activator of the Keap1/Nrf2/ARE pathway, acting as a non-competitive inhibitor of AChE with an IC50 of 14.79 µM and a Ki of 1.35 µM. It enhances Nrf2 nuclear translocation, thereby upregulating antioxidant gene expression and boosting cellular defenses against oxidative stress. In PC12 cells, Keap1/Nrf2/ARE activator 2 demonstrates significant neuroprotective effects against damage induced by H2O2 and Scopolamine (SCA). In zebrafish models, it alleviates cognitive deficits and neuroinflammation associated with SCA-induced impairments. This compound is relevant for Alzheimers disease research.
