QND8 is a selective and potent agonist of the alpha7 nicotinic acetylcholine receptor (nAChR). It alleviates thermal hyperalgesia and mechanical allodynia in carrageenan-induced inflammatory pain in mice. QND8 also reduces paw swelling, inhibits the release of pro-inflammatory factors at inflammation sites, and prevents leukocyte infiltration. It is applicable in research on inflammatory and neurological diseases, like arthritis.
Molecular Weight:
270.34
CAS Number:
[1778682-60-2]
Formula:
C15H18N4O
Target:
AChR
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