alpha-Tubulin polymerization-IN-1 Preis auf Anfrage

Catalog Number: TGM-T206470
Article Name: alpha-Tubulin polymerization-IN-1 Preis auf Anfrage
Biozol Catalog Number: TGM-T206470
Supplier Catalog Number: T206470
Alternative Catalog Number: TGM-T206470-10MG,TGM-T206470-50MG
Manufacturer: TargetMol
Category: Biochemikalien
alpha-Tubulin polymerization-IN-1 (Compound 8l) functions as an inhibitor of alpha-tubulin polymerization. This compound modulates the NRF2/KEAP-1 signaling pathway and induces ROS production in PC-3 cells, leading to apoptosis. It inhibits the proliferation of PC-3 cells with a GI50 of 0.17 µM, causing cell cycle arrest in the G2/M phase. Additionally, alpha-Tubulin polymerization-IN-1 demonstrates antitumor activity in mouse models.
Target: Apoptosis|||ROS|||Reactive Oxygen Species|||Nrf2|||Microtubule Associated