NtPPO-IN-1 (Compound A4) is an inhibitor of Nicotiana tabacum PPO (NtPPO) with a Ki of 9.05 nM. It exhibits herbicidal activity against Setaria viridis, Echinochloa crus-galli, Digitaria sanguinalis, Amaranthus retroflexus, Abutilon theophrasti, and Portulaca oleracea, causing 30-50% damage to corn and rice at 150 g a.i./ha.
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