anti-NSCLC agent-1 (compound 8dc) is an inhibitor of tyrosine kinase inhibitors (TKI), and demonstrates IC50 values of 0.05 µM in A549 cells and 0.09 µM in NCI-H441 cells. It exhibits anti-NSCLC activity by inhibiting colony formation, as well as cell migration and invasion.
Target:
EGFR
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