CP5V is a rationally designed PROTAC molecule composed of ligands for von Hippel-Lindau and cyclin-dependent kinase, which selectively induces degradation of Cdc20 by tethering it to the VHL/VBC E3 ligase complex, leading to ubiquitination and proteasomal degradation, mitotic arrest, and suppression of cancer cell proliferation, thereby serving as a mechanistic tool for cell cycle and oncology research.
Molecular Weight:
1075.5
Purity:
99.95%
CAS Number:
[2509359-75-3]
Formula:
C46H66Cl3N9O12S
Target:
APC/C|||PROTACs
T10875
T10875
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