Penicilloyl-transferrin conjugate was used as the immunogen for the Penicillin antibody.
This antibody reacts mainly with the hiazolidine ring of penicillin, but not with the lactam ring. May react with the fused beta lactam/thiazolidine ring of the penicilloyl group and would appear sensitive to modification of the shared N atom of the lactam/thiazolidine ring by substitution or conjugation. It appears insensitive to the structure of the side chain of the penicilloyl group. This antibody reacts with the following penicillin, Benzylpenicillin, Ampicillin, Amoxicillin and 6-Aminopenicillanic acids. Penicillin is a group of Beta-lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. -lactam antibiotics work by inhibiting the formation of peptidoglycan cross-links in the bacterial cell wall, which results in cytolysis. This antibody is useful in the study of allergy to penicillin.
Clonality:
Monoclonal
Clone Designation:
[Pen-9]
UniProt:
Not Applicable
Purity:
Protein A/G affinity
Form:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Antibody Type:
Primary Antibody
Application Dilute:
ELISA: 1-5ug/ml (order BSA-free format for coating)
Application Notes:
Optimal dilution of the Penicillin antibody should be determined by the researcher.
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