Granzyme B Antibody, Clone: [GZB-1], Mouse, Monoclonal
Biozol Catalog Number:
NSJ-V7638SAF-100UG
Supplier Catalog Number:
V7638SAF-100UG
Alternative Catalog Number:
NSJ-V7638SAF-100UG
Manufacturer:
NSJ Bioreagents
Host:
Mouse
Category:
Antikörper
Application:
IHC-P, WB
Species Reactivity:
Human
Immunogen:
Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]
