Recombinant human protein was used as the immunogen for the CD70 antibody.
It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Antibody Type:
Primary Antibody
Application Dilute:
ELISA (order BSA/sodium azide-free format for coating),Functional studies (order BSA/sodium azide-free format),Flow cytometry: 1-2ug/10 6 cells,Immunofluorescence: 1-2ug/ml
Application Notes:
The concentration stated for each application is a general starting point. Optimal dilution of the CD70 antibody should be determined by the researcher.
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