GRP94 Antibody / HSP90B1, Clone: [9G10.F8.2], Rat, Monoclonal
Biozol Catalog Number:
NSJ-V2908IHC-7ML
Supplier Catalog Number:
V2908IHC-7ML
Alternative Catalog Number:
NSJ-V2908IHC-7ML
Manufacturer:
NSJ Bioreagents
Host:
Rat
Category:
Antikörper
Application:
IHC-P
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Purified glucose regulated protein 94 from chicken oviducts was used as the immunogen for the GRP94 antibody.
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This mAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*
Antibody Type:
Primary Antibody
Application Dilute:
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Application Notes:
Optimal dilution of the GRP94 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
* VAT and and shipping costs not included. Errors and price changes excepted
