An amino acid sequence from the N-terminus of human Bcl2A1 (MTDCEFGYIYRLAQDY) was used as the immunogen for this Bcl2A1 antibody.
Bcl-2-related protein A1(BCL2A1), is the human homolog of the murine A1, and maps to chromosome 15q24.3. The BCL2A1 gene has also been referred to as BCL2L5, BFL1, and GRS. Bfl-1 protein suppresses apoptosis induced by the p53 tumor suppressor protein in a manner similar to other Bcl-2 family members such as Bcl-2, Bcl-xL and EBV-BHRF1. In addition, the bfl-I gene cooperates efficiently with the Ela oncogene in transformation of primary rodent epithelial cells. The human bfl-1 gene may play an important role in carcinogenesis.
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Purity:
Antigen affinity
Form:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Antibody Type:
Primary Antibody
Application Dilute:
Western blot: 0.5-1ug/ml
Application Notes:
The stated application concentrations are suggested starting points. Titration of the Bcl2A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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