An amino acid sequence from the C-terminus of human A Disintegrin and Metalloproteinase Domain 2 (VLIAIMVKVNFQRKK) was used as the immunogen for this ADAM2 antibody.
A Disintegrin and Metalloproteinase Domain 2, also known as FTNB or PH30, is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Burkin et al.(1997) used fluorescence in situ hybridization to map the FTNB gene to 8p11.2.
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Purity:
Antigen affinity
Form:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Antibody Type:
Primary Antibody
Application Dilute:
Western blot: 0.5-1ug/ml
Application Notes:
The stated application concentrations are suggested starting amounts. Titration of the ADAM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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