An amino acid sequence from the C-terminus of human Leukocyte tyrosine kinase (RGLQPQNLWNPTYRS) was used as the immunogen for this LTK antibody.
Leukocyte tyrosine kinase, also known as TYK1, is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Toyoshima et al.(1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs. Liao et al.(1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2. Thus, the gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions.
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Purity:
Antigen affinity
Form:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Antibody Type:
Primary Antibody
Application Dilute:
Western blot: 0.5-1ug/ml
Application Notes:
The stated application concentrations are suggested starting amounts. Titration of the LTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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