A portion of amino acids 271-298 from the human protein was used as the immunogen for the LGALS8 antibody.
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.
The stated application concentrations are suggested starting points. Titration of the LGALS8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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