A portion of amino acids 86-113 from the mouse protein was used as the immunogen for the c-Raf antibody.
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3 (By similarity).
The stated application concentrations are suggested starting points. Titration of the c-Raf antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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