A portion of amino acids 78-107 from the mouse protein was used as the immunogen for the Pyruvate dehydrogenase kinase 2 antibody.
Pdk2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:2000
Application Notes:
The stated application concentrations are suggested starting points. Titration of the Pyruvate dehydrogenase kinase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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