A portion of amino acids 54-82 from the human protein was used as the immunogen for the COL5A1 antibody.
COL5A1 encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. COL5A1 product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq].
The stated application concentrations are suggested starting points. Titration of the COL5A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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