CBS Antibody / Cystathionine Beta Synthase, Rabbit, Polyclonal
Biozol Catalog Number:
NSJ-F54306-0.08ML
Supplier Catalog Number:
F54306-0.08ML
Alternative Catalog Number:
NSJ-F54306-0.08ML
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
FACS, IF, IHC-P, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
A portion of amino acids 301-330 from the human protein were used as the immunogen for the CBS antibody.
CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.
Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:25,Immunofluorescence: 1:25,Flow cytometry: 1:25 (1x10e6 cells)
Application Notes:
The stated application concentrations are suggested starting points. Titration of the CBS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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