A portion of amino acids 132-161 from the human protein were used as the immunogen for the CDC73 antibody.
CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3 mRNA processing factors with actively-transcribed chromatin.
Western blot: 1:1000-1:2000,Immunohistochemistry (FFPE): 1:25,Flow cytometry: 1:25 (1x10e6 cells),Immunofluorescence: 1:25
Application Notes:
The stated application concentrations are suggested starting points. Titration of the CDC73 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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