A portion of amino acids 218-252 from human TMEM106B was used as the immunogen for the TMEM106B antibody.
Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching. [UniProt]
The stated application concentrations are suggested starting points. Titration of the TMEM106B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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