A human recombinant partial protein was used as the immunogen for this MAPK14 / p38 MAPK antibody.
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.
The stated application concentrations are suggested starting points. Titration of the p38 MAPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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