A partial recombinant protein corresponding to amino acids 200-420 from the human protein was used as the immunogen for the NPR3 antibody.
Natriuretic Peptide Receptor 3/C is the receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
