A portion of amino acids 33-64 from the human protein was used as the immunogen for the AKR7A3 antibody.
Aflatoxin B1 aldehyde reductase member A3 can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.