A portion of amino acids 243-276 from the human protein was used as the immunogen for the LIPF antibody.
The LIPF gene encodes gastric lipase or Lipase F, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. [RefSeq]