A portion of amino acids 104-132 from the human protein was used as the immunogen for this CGRP antibody.
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.