ANGPTL3 Antibody / Angiopoietin-like protein 3, Rabbit, Polyclonal
Biozol Catalog Number:
NSJ-F49810-0.08ML
Supplier Catalog Number:
F49810-0.08ML
Alternative Catalog Number:
NSJ-F49810-0.08ML
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, WB
Species Reactivity:
Human, Mouse
Immunogen:
A portion of amino acids 82-114 from the human protein was used as the immunogen for this ANGPTL3 antibody.
ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
