CUX1 Antibody / Homeobox protein cut-like 1, Rabbit, Polyclonal
Biozol Catalog Number:
NSJ-F49389-0.08ML
Supplier Catalog Number:
F49389-0.08ML
Alternative Catalog Number:
NSJ-F49389-0.08ML
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, IF, IHC, WB
Species Reactivity:
Human
Immunogen:
A portion of amino acids 1347-1374 from the human protein was used as the immunogen for this CUX1 antibody.
CUX1 likely has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5 and 3) of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). [UniProt]
