This phospho-Nephrin antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY1193 of human Nephrin.
Nephrin a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. It primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine.
