Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as coagulation type[1].
Molecular Weight:
883.02 (free base)
Purity:
99.78
Formula:
C42H63FN12O8.xC2HF3O2
Target:
Protease Activated Receptor (PAR)
Application Notes:
MCE Product type: Peptides
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