Chemical Name: 4-[1,1-Biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester
TGFbeta inhibitor
Molecular Weight:
415.53
Purity:
>98% by HPLC NMR (Conforms)
Form:
Yellow solid
CAS Number:
[1099644-42-4]
Formula:
C27H29NO3
Application Notes:
ITD-1 (1099644-42-4) is a selective inhibitor of TGFß signaling (IC50=0.85 µM).1 Induces proteasomal degradation of TGFß type II receptor. Induces cardiomyocyte differentiation in embryonic stem cells.1,2
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