This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],function:Might be involved in angiogenesis inhibition.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 4 TSP type-1 domains.,subunit:Interacts with GABPB2.,tissue specificity:Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.,
