Cathepsin K Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE86987
Supplier Catalog Number:
AMRe86987
Alternative Catalog Number:
EKL-AMRE86987-50UL,EKL-AMRE86987-100UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
Unconjugated
Alternative Names:
CTSO, PKND, PYCD, CTS02, CTSO1, CTSO2
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
