PMEL/Melanoma gp100(HMB45) Mouse Monoclonal Antibody, Unconjugated
Catalog Number:
EKL-AMM22168
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| Article Name: | PMEL/Melanoma gp100(HMB45) Mouse Monoclonal Antibody, Unconjugated |
| Biozol Catalog Number: | EKL-AMM22168 |
| Supplier Catalog Number: | AMM22168 |
| Alternative Catalog Number: | EKL-AMM22168-50UL, EKL-AMM22168-100UL |
| Manufacturer: | EnkiLife |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA, IHC |
| Species Reactivity: | Human, Mouse |
| Conjugation: | Unconjugated |
| Alternative Names: | 95 kDa melanocyte specific secreted glycoprotein,95 kDa melanocyte-specific secreted glycoprotein,D12S53E,gp100,M-beta,ME20,ME20 M/ME20 S,ME20-M,ME20-S,ME20M,ME20M/ME20S,ME20S,Melanocyte lineage specific antigen GP100,Melanocyte protein mel 17,Melanocyte protein Pmel 17,Melanocyte protein Pmel 17 precursor,Melanocytes lineage-specific antigen GP100,Melanoma associated ME20 antigen,Melanoma gp100,Melanoma-associated ME20 antigen,Melanosomal matrix protein 17,Melanosomal matrix protein17,P1,p100,p26,PMEL 17,PMEL,PMEL_HUMAN,PMEL17,Premelanosome protein,Secreted melanoma-associated ME20 antigen,SI,SIL,SILV,Silver,mouse homolog,like,Silver homolog,Silver locus protein homolog,HMB45, |
| This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011], |
| Clonality: | Monoclonal |
| Molecular Weight: | Calculated MW:70kDa,Observed MW:80kDa |
| UniProt: | P40967 |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Form: | Liquid |
| Target: | PMEL D12S53E PMEL17 SILV |
| Application Dilute: | IHC 1:200-400,ELISA 1:500-5000 |
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AMM22168 |
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