pCR8 is a prodrug of CR8. It exhibits amphiphilic properties, enabling self-assembly into nanoparticles. Under high concentrations of H2O2 in the tumor microenvironment, pCR8 releases CR8. CR8 functions as a molecular glue degrader, effectively breaking down cell cycle-related proteins and possessing anti-tumor activity. pCR8 is applicable in research on cancers such as breast cancer.
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