MDMX/MDM2-IN-2 is a potent dual inhibitor of MDM2 and MDMX, with Kis of 0.23 µM and 2.45 µM respectively. It reactivates p53 function, inducing cell cycle arrest and apoptosis in vitro, and demonstrates anti-metastatic and antitumor activity in cancer research models.
Molecular Weight:
576.87
Formula:
C28H25Cl3FN3O3
Target:
Apoptosis,MDM-2/p53,Others
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